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Safety and Compliance — Phlebotomy Technician Certification practice questions

37 multiple-choice questions and 16 flashcards on Safety and Compliance, about 22% of the Phlebotomy Technician Certification bank. Every one carries a written rationale.

Written and maintained by Nick Burton · last updated 2026-08-22 · how we write and review questions

What this chapter covers

Safety and Compliance is one of 5 chapters in CoStudy's Phlebotomy Technician Certification bank, and it holds 37 of the bank's 166 multiple-choice questions — roughly 22% of the total. That proportion is not arbitrary: chapters follow the certifying body's published exam outline, and the number of questions in each is set by that domain's published weight, so the share of your practice time this chapter takes matches the share of the real exam it accounts for.

Studying by chapter is worth doing once you have a diagnostic score. A single overall percentage tells you whether you are close; it does not tell you which domain is dragging. Working a weak chapter in isolation, and re-testing it in isolation, is the fastest way to move a score that has stalled — and it is why the mock exams in CoStudy report by domain rather than as one number.

Free Safety and Compliance practice questions

10 questions drawn from this chapter, with the full rationale shown — the controlling principle behind the right answer, and why each wrong option tempts and fails.

A control sample with a known concentration is used to:

  1. Replace patient samples
  2. Calibrate billing
  3. Discard
  4. Verify analyzer accuracy and precision

Answer: D — Verify analyzer accuracy and precision

A/B/C) Wrong. D) Correct.

Hepatitis B vaccine should be offered to phlebotomists:

  1. Free of charge, within 10 days of starting work
  2. Only after exposure
  3. Only upon request after 1 year
  4. Never

Answer: A — Free of charge, within 10 days of starting work

A) Correct — OSHA mandate. B/C/D) Wrong.

Engineered sharps injury protection devices are required by:

  1. The CDC voluntary program
  2. The OSHA Needlestick Safety and Prevention Act
  3. FDA only
  4. State boards

Answer: B — The OSHA Needlestick Safety and Prevention Act

A) Guidance. B) Correct — 2000 federal law. C/D) Wrong.

In the event of a chemical spill in the lab, the appropriate resource to consult is:

  1. The patient chart
  2. The Safety Data Sheet (SDS)
  3. The phone book
  4. The lab supervisor's email

Answer: B — The Safety Data Sheet (SDS)

A/C/D) Wrong. B) Correct.

Hand sanitizer is most effective when:

  1. Hands are visibly soiled
  2. Used on top of gloves
  3. Diluted with water
  4. Hands are not visibly soiled — otherwise wash with soap and water

Answer: D — Hands are not visibly soiled — otherwise wash with soap and water

A) Wash first. B/C) Wrong. D) Correct — CDC guidance.

CLIA stands for:

  1. Centers for Laboratory Improvement Agency
  2. Certified Lab Inspection Act
  3. Clinical Lab Industry Association
  4. Clinical Laboratory Improvement Amendments

Answer: D — Clinical Laboratory Improvement Amendments

A/B/C) Wrong. D) Correct — 1988 federal law.

Chain of custody is most important for:

  1. Routine CBC
  2. Forensic and drug-screen samples
  3. Glucose testing
  4. Cholesterol testing

Answer: B — Forensic and drug-screen samples

A/C/D) Standard chain of accountability sufficient. B) Correct.

POCT (point-of-care testing) quality requires:

  1. Regular control runs and operator competency documentation
  2. No QC at all
  3. Annual checks only
  4. Manufacturer testing only

Answer: A — Regular control runs and operator competency documentation

A) Correct. B/C/D) Inadequate.

Standard precautions are based on the principle that:

  1. All blood and body fluids are treated as potentially infectious
  2. Only known infectious patients require precautions
  3. Only patients with HIV require protection
  4. Gloves alone are sufficient

Answer: A — All blood and body fluids are treated as potentially infectious

A) Correct. B/C/D) Wrong.

Quality assurance (QA) differs from quality control (QC) in that QA:

  1. Refers to instrument calibration only
  2. Replaces QC
  3. Means nothing
  4. Encompasses the entire pre-, analytical, and post-analytical process

Answer: D — Encompasses the entire pre-, analytical, and post-analytical process

A) Narrow. B/C) Wrong. D) Correct — system-wide.

Safety and Compliance flashcards

2 cards from the 16 in this chapter.

Phlebotomy role?

Collect blood specimens for diagnostic testing, transfusion, research, or donation. Work in hospitals, outpatient labs, donation centers, physician offices.

PPE for phlebotomy?

Gloves mandatory. Lab coat. Face shield/mask + eye protection for splash risk (line draws, anticipated bleeders). Change gloves between patients.

Practise the full chapter

These are a sample. The full Safety and Compliance chapter runs 53 items with per-chapter progress tracking, on the web and in the iOS app.

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